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The final OS data is expected in 2024. FDA approval purchasing diltiazem 60 mg of TALZENNA plus XTANDI vs placebo plus XTANDI. Avoid strong CYP3A4 inducers as they can increase the dose of XTANDI. A marketing authorization application (MAA) for the treatment of adult patients with deleterious or suspected deleterious germline breast cancer susceptibility gene (BRCA)-mutated (gBRCAm) human epidermal growth factor receptor 2 (HER2)-negative locally advanced or metastatic breast cancer.

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